Andy,
How thick is the current plywood floor? How many pieces? Do they go out beyond the shower? Are they glued to the joists? Can you screw them to the joists? Without seeing the situation, I would consider an additional layer of 3/4" ply glued and screwed to the existing floor AND the floor joists, then do your leveling being sure to completely support the the pan.
And, yes, you can put a solid surface pan on a wood floor system if it is a good pan and a good floor.